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Immunotherapy

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16.06.2022
20:12 News-Medical.Net Oral immunotherapy for peanut allergies is highly effective when started for infants under 12 months

UBC researchers demonstrated in 2019 that pre-schoolers can safely overcome peanut allergies with a treatment called oral immunotherapy.

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15:04 CancerNetwork.com Richard Kim, MD, on Future Research Efforts With Immunotherapy Combos in Metastatic CRC

Richard Kim, MD, highlights future research efforts examining immunotherapy/chemotherapy combinations for patients with metastatic colorectal cancer.

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11.06.2022
01:10 ScienceDaily.com Immunotherapy may get a boost

T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells. Researchers now describe what inhibits this immune function and how they can release the brake and boost the immune response against cancer.

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10.06.2022
21:10 ScienceDaily.com Dogs inhale immunotherapy to test lung cancer treatment

An inhaled immunotherapy successfully treated cancer in some companion dogs as part of a clinical trial conducted by oncology and veterinary researchers. Results show potential for fighting cancer in humans as well.

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11:33 Technology.org Promising Results for Chemo Immunotherapy Combination Against Pancreatic Cancer

A combination of chemotherapy with immunotherapy meant to unleash the anticancer capacity of the immune system was effective

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09.06.2022
21:22 News-Medical.Net Researchers demonstrate the double advantage of killer T-cells used in cancer immunotherapy

To grow, tumors rely on a specific structure, the tumor stroma. This includes blood vessels, which provide the nutrients necessary for the multiplication of diseased cells, and of lymphatic vessels, through which they migrate to metastasize.

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08.06.2022
23:04 CancerNetwork.com Biagio Ricciuti, MD, Reviews Combination Immunotherapy Regimens in NSCLC

Biagio Ricciuti, MD, spoke about combination immunotherapy regimens for patients with non–small cell lung cancer who did not respond well to prior treatment.

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19:41 News-Medical.Net Black, Hispanic patients with advanced liver cancer have lower chance of receiving immunotherapy

Racial and ethnic minorities diagnosed with advanced liver cancer have a lower chance of receiving immunotherapy, the most effective treatment for patients with the disease, according to a new study led by Cedars-Sinai Cancer investigators.

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14:03 Nanowerk.com Microbubble technology enhances cancer immunotherapy

Scientists have developed a first-of-its-kind ultrasound-guided cancer immunotherapy platform that delivers immune-stimulating agents to cells for the development of systemic anti-tumor immunity.

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07.06.2022
15:33 AzoNano.com New Microbubble-Assisted Ultrasound-Guided Immunotherapy Could Improve Treatment of Cancer Patients

Researchers at UT Southwestern have developed a first-of-its-kind ultrasound-guided cancer immunotherapy platform that delivers immune-stimulating agents to cells for the development of systemic...

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08:23 News-Medical.Net New microbubble-assisted ultrasound-guided immunotherapy helps improve anti-tumor immunity

Researchers at UT Southwestern have developed a first-of-its-kind ultrasound-guided cancer immunotherapy platform that delivers immune-stimulating agents to cells for the development of systemic anti-tumor immunity.

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00:42 News-Medical.Net Chemo-immunotherapy combination shows promise against pancreatic cancer

A combination of chemotherapy with an immunotherapy meant to unleash the anticancer capacity of the immune system was effective against one of the hardest targets in cancer care, pancreatic cancer, in a national, randomized clinical trial led by researchers at the Perelman School of Medicine at the University of Pennsylvania, and sponsored by the Parker Institute for Cancer Immunotherapy.

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06.06.2022
16:42 News-Medical.Net New trial examines the effectiveness of combination immunotherapy for platinum-resistant ovarian cancer

A new clinical trial studying the effectiveness of a combination of immunotherapy treatments could be more effective for patients with ovarian cancer who are resistant to traditional interventions.

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03.06.2022
14:32 News-Medical.Net Liquid biopsy could better predict immunotherapy response in lung cancer patients than tumor biopsy

Mount Sinai researchers have validated for the first time that a simple blood test called a liquid biopsy could be a better predictor of whether cancer immunotherapy will be successful for a patient with lung cancer than an invasive tumor biopsy procedure.

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02.06.2022
20:32 News-Medical.Net Aerobic exercise amplifies the effects of immunotherapy to reduce pancreatic tumor growth

Aerobic exercise reprograms the immune system to reduce pancreatic tumor growth and amplify the effects of immunotherapy, a new study finds.

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12:41 Nature.Com Designer protein circuits enable safe cancer immunotherapy

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05:12 News-Medical.Net New "masked" version of immunotherapy could help fight cancer without causing side effects

Many cancer treatments are notoriously savage on the body; they attack healthy cells at the same time as tumor cells, causing a plethora of side effects.

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31.05.2022
17:20 ScienceDaily.com Discovery could lead to better cancer immunotherapy

A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body's defenses against cancerous tumors. The discovery could lead to more effective cancer immunotherapy, a promising treatment which uses the body's own immune system, rather than radiation, to attack cancer cells. In an animal study, researchers found that a population of T cells called CD4-positive helper T cells helped start a chain of antitumor immunity defenses that allow killer cells to better infiltrate melanoma and breast cancer tumors.

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16:32 News-Medical.Net New discovery could pave the way for more effective cancer immunotherapy

A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body's defenses against cancerous tumors.

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07:42 News-Medical.Net New compounds for cancer immunotherapy via STING-mediated immune activation

Innovations in cancer immunotherapy have achieved clinical success by considerably increasing the survival rate of patients undergoing cancer treatment.

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30.05.2022
21:10 ScienceDaily.com Ultrasound-guided microbubbles boost immunotherapy efficacy

Researchers have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.

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19:13 Phys.org Ultrasound-guided microbubbles boost immunotherapy efficacy

Researchers at The University of Texas MD Anderson Cancer Center have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade. The findings from the preclinical study were published today in Nature Nanotechnology.

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18:43 Nanowerk.com Ultrasound-guided microbubbles boost immunotherapy efficacy

Researchers developed a platform to improve both antitumor immune responses and responses to checkpoint inhibitors.

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17:13 Nanowerk.com Multifunctional nanoplatform for efficient cancer photo-immunotherapy

Researchers developed a multifunctional nanoplatform based on mesoporous hexagonal core-shell zinc porphyrin-silica nanoparticles (MPSNs) loaded with R837 (a toll-like receptor-7 agonist), which can be used to integrate PDT, PTT, and tumor-specific immunotherapy for breast cancer.

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17:03 Phys.org Light-triggered multifunctional nanoplatform for efficient cancer photo-immunotherapy

Cancer immunotherapy is a treatment modality against tumor growth and metastasis via stimulating host immune responses. Phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), is a less invasive treatment compared to chemotherapy. To be specific, PDT and PTT-induced immunogenic cell death can release tumor-associated antigens and damage-associated molecular patterns, stimulating an immune response.

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27.05.2022
04:10 NewScientist.Com Brain cancer immunotherapy in mice more effective with drug coating

A nanoparticle coat helps an immunotherapy drug cross the blood-brain barrier in mice so it can target brain tumours more effectively

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26.05.2022
05:42 News-Medical.Net New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.

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25.05.2022
18:50 Nature.Com ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

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17:53 AzoNano.com Improving Nucleic Acid Delivery for Immunotherapy Applications

Scientists have recently assessed that substituting hydroxycholesterol candidates in ionizable nanoparticles could elevate the possibility of messenger RNA (mRNA) delivery to T cells. This finding...

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08:05 News-Medical.Net Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

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05:06 Arxiv.org Quantitative Biology A mathematical model of Breast cancer (ER+) with excess estrogen: Mixed treatments using Ketogenic diet, endocrine therapy and Immunotherapy. (arXiv:2205.11974v1 [math.DS])

Breast Cancer is a major public health problem and the most common diagnosed malignancy in woman. There have been significant developments in clinical approaches and theoretical experimental to understand the interactions of cancer cells dynamics with the immune system, also developments on analytical and computational models to help provide insights into clinical observations for a better understanding of cancer cells, but more are needed, especially at the genetic and molecular levels mathematically. Treatments such as immunotherapy, chemotherapy, hormone therapy, radiotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of estrogen derived from recent models, but this time combined with immunotherapy as a way to treat or inhibit the cancer growth by a mathematical model of breast cancer in situ, governed by a simplified model of nonlinear-coupled ordinary differential equations, that combines

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05:06 Arxiv.org Math A mathematical model of Breast cancer (ER+) with excess estrogen: Mixed treatments using Ketogenic diet, endocrine therapy and Immunotherapy. (arXiv:2205.11974v1 [math.DS])

Breast Cancer is a major public health problem and the most common diagnosed malignancy in woman. There have been significant developments in clinical approaches and theoretical experimental to understand the interactions of cancer cells dynamics with the immune system, also developments on analytical and computational models to help provide insights into clinical observations for a better understanding of cancer cells, but more are needed, especially at the genetic and molecular levels mathematically. Treatments such as immunotherapy, chemotherapy, hormone therapy, radiotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of estrogen derived from recent models, but this time combined with immunotherapy as a way to treat or inhibit the cancer growth by a mathematical model of breast cancer in situ, governed by a simplified model of nonlinear-coupled ordinary differential equations, that combines

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23.05.2022
22:44 CancerNetwork.com ASCO GU 2022 Updates: Trials on Combination Immunotherapy versus Chemotherapy

Petros Grivas, MD, PhD, transitions the panel discussion to focus on clinical trial data on combination immunotherapy versus platinum chemotherapy regimens that were recently presented at ASCO GU 2022.

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20.05.2022
20:12 News-Medical.Net Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

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18.05.2022
23:50 ScienceDaily.com Researchers discover effective combination immunotherapy for liver cancer

Researchers have discovered a specific combination immunotherapy that shows promise in the fight against liver cancer.

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16.05.2022
22:04 Drugs.com Immunotherapy With Nivolumab (Opdivo) Can Lower Recurrence When Bladder Cancer Spreads

MONDAY, May 16, 2022 -- Immunotherapy with nivolumab (Opdivo) after surgery for metastatic bladder cancer significantly reduces the odds for the tumor's return, a new clinical trial finds. Among 700 patients with urothelial cancer of the bladder or...

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18:44 Drugs.com Immunotherapy Drug Can Lower Recurrence When Bladder Cancer Spreads

MONDAY, May 16, 2022 -- Immunotherapy with nivolumab (Opdivo) after surgery for metastatic bladder cancer significantly reduces the odds for the tumor's return, a new clinical trial finds. Among 700 patients with urothelial cancer of the bladder or...

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16:01 News-Medical.Net Immunotherapy combined with chemoradiation and surgery could help treat nonmetastatic gastroesophageal cancer

Immunotherapy has transformed treatment for patients with stage 4 metastatic esophageal and gastric cancers. In patients with these malignancies, immunotherapy has been shown to prolong survival when patients' tumors exhibit a high expression of an immune-related protein called PD-L1.

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15.05.2022
22:12 News-Medical.Net Immunotherapy after bladder cancer surgery helps reduce cancer recurrence

Immunotherapy after surgery helped reduce cancer recurrence in patients with urothelial cancer of the bladder or other sites in the urinary tract that had invaded the muscle and therefore posed a high risk for recurrence, according to clinical trial results presented at the American Urological Association annual meeting in May.

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13.05.2022
16:24 CancerNetwork.com IMpower010 and KEYNOTE-091: Adjuvant Immunotherapy in NSCLC

Expert perspectives on the IMpower010 and KEYNOTE-091 trials, which assessed adjuvant immunotherapy in non–small cell lung cancer.

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12.05.2022
00:52 News-Medical.Net World's first Focused Ultrasound Cancer Immunotherapy Center could revolutionize cancer care

UVA Health and the Charlottesville-based Focused Ultrasound Foundation today announced the launch of the Focused Ultrasound Cancer Immunotherapy Center, the world's first center dedicated specifically to advancing a focused ultrasound and cancer immunotherapy treatment approach that could revolutionize 21st-century cancer care.

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11.05.2022
11:03 Technology.org T cell behavior determines immunotherapy success

Immunotherapy unleashes the power of the immune system to fight cancer, but for some patients, immunotherapy doesn’t work.

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10.05.2022
14:33 Technology.org New discovery could help combat side effects of cancer immunotherapy

Researchers in Liverpool and the US have made a breakthrough that could lead to improved immunotherapy treatments for

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09.05.2022
20:42 News-Medical.Net Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy

Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6).

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19:50 ScienceDaily.com Targeting interleukin-6 could help relieve immunotherapy side effects

Researchers have identified a novel strategy to reduce immune-related adverse events from immunotherapy treatment by targeting the cytokine interleukin-6 (IL-6).

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06.05.2022
16:24 CancerNetwork.com Role of Immunotherapy in Newly Diagnosed NSCLC

A broad discussion on the role of immunotherapy in newly diagnosed NSCLC in both the neoadjuvant and adjuvant settings.

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00:20 ScienceDaily.com Breaking the shield that protects pancreatic cancer from immunotherapy

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study suggests. The findings could offer a new strategy to fight pancreatic cancer, a deadly disease for which no truly effective treatments exist.

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05.05.2022
16:51 News-Medical.Net Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

It's not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.

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28.04.2022
21:23 AzoNano.com E. Coli Nanomaterial Aids Cancer Photothermal and Immunotherapy

A recent article published in the journal ACS Nano discusses the application of Escherichia coli (E. coli)-mimetic nanomaterials for photolytic treatment of CT-26 or 4T1 tumors....

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15:52 AzoNano.com Study Helps Validate Cowpea Mosaic Virus Nanoparticle as the Lead Cancer Immunotherapy Candidate

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the...

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15:41 News-Medical.Net Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

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26.04.2022
03:31 News-Medical.Net A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

The development of the anti-cancer immunotherapy drugs called immune checkpoint inhibitors has improved treatment for many cancer patients, but patients with mucosal melanomas -; melanomas that occur not on the skin but in the mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region -; are particularly resistant to immune checkpoint inhibitors for reasons researchers don't fully understand.

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22.04.2022
15:54 Drugs.com New Combo Immunotherapy Prolongs Survival in Patients With Advanced Kidney Cancer

FRIDAY, April 22, 2022 -- The use of immunotherapy and/or targeted drugs revolutionized the treatment of many cancers, but some people grow resistant to immunotherapy drugs and relapse as a result. For cases of advanced kidney cancer, a new drug in...

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21.04.2022
21:13 FierceBiotech.com Genentech-led team uncovers how cancer cells resist T cell attack in potential boon to immunotherapy

Genentech-led team uncovers how cancer cells resist T cell attack in potential boon to immunotherapy aliu Thu, 04/21/2022 - 06:11

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18:13 CancerNetwork.com The Role of Biomarkers in Immunotherapy Selection for mUC

Experts discuss the role of biomarkers in treatment selection for patients with metastatic UC.

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03:51 News-Medical.Net Newly discovered immune cell "soldier" could be a good target for immunotherapy

Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to these treatments. There is need for continued research.

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20.04.2022
21:50 ScienceDaily.com Scientists identify potential new 'soldier' for cancer immunotherapy

The new cells, which the scientists have dubbed killer innate-like T cells, differ in several notable ways from the conventional target of many immunotherapies.

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08:04 BusinessKorea.co.kr KIST and KRICT Jointly Develop New Cancer Immunotherapy

The Korea Institute of Science and Technology (KIST) and the Korea Research Institute of Chemical Technology (KRICT) announced on April 19 that they have developed a new cancer immunotherapy for inhibiting cancer cell growth by helping immunocytes penetrate cancer cells.The interferon gene promoter

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19.04.2022
18:20 ScienceDaily.com Particles released by red blood cells are effective carriers for anti-cancer immunotherapy

A study has demonstrated that nano-sized vesicles released by red blood cells are a viable platform for delivering immunotherapeutic RNA molecules to suppress breast cancer growth and metastasis. The study successfully delivered RIG-I-activating RNAs using small, lipid membrane-bound particles released by red blood cells, called red blood cell extracellular vesicles (RBCEVs), to suppress cancer progression. The team had also discovered in earlier studies that these vesicles are ideal therapeutic carriers with a natural ability to deliver bioactive molecules to many cell types.

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18.04.2022
19:44 CancerNetwork.com Real-world Treatment Patterns and Clinical Outcomes in Patients Treated With Eribulin After Prior Immunotherapy (IO) or Antibody-Drug Conjugate (ADC) for Metastatic Breast Cancer

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15.04.2022
20:20 ScienceDaily.com Study reveals male sex hormones are new targets for cancer immunotherapy

A study examined the differences in intratumoral immune responses between male and female cancers of non-reproductive origin.

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14.04.2022
21:21 ScienceDaily.com Vitamin E can boost immunotherapy responses by reinvigorating dendritic cells

Using retrospective clinical data and in-depth lab studies, researchers have discovered that vitamin E can enhance immunotherapy responses by stimulating dendritic cells in the tumor.

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12.04.2022
18:03 Technology.org How Ovarian Cancer Defies Immunotherapy

Researchers at the University of California San Diego School of Medicine and Moores Cancer Center at UC San

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17:21 News-Medical.Net Researchers elucidate how ovarian tumors defy immunotherapy

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health, with collaborators at La Jolla Institute for Immunology and elsewhere, have further elucidated how ovarian cancer tumors defy immunotherapy, identifying new molecular targets that might boost immune response.

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11.04.2022
20:41 News-Medical.Net Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients

Adding the immunotherapy drug nivolumab to chemotherapy before surgery (neoadjuvant) for patients with operable non-small cell lung cancer (NSCLC) — the leading cause of cancer deaths worldwide — reduced the risk of recurrence of the cancer or death by more than one-third, according to results from the phase III CheckMate-816 trial.

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04:01 News-Medical.Net Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

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09.04.2022
06:01 News-Medical.Net Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma

Patients with advanced melanoma whose cancer does not respond to treatment with widely used immunotherapy drugs known as PD-1 inhibitors are often switched to treatment with a second type of immunotherapy drug – a CTLA-4 inhibitor such as the drug ipilimumab.

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08.04.2022
15:03 CancerNetwork.com OncView™ Podcast: Immunotherapy Response Monitoring in Melanoma

John Kirkwood, MD, PhD, discussed considerations for treating patients with melanoma using immunotherapy and how to properly monitor responses.

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05.04.2022
11:02 FierceBiotech.com New targets could mean better immunotherapy for colon cancer

New targets could mean better immunotherapy for colon cancer ssorensen Mon, 04/04/2022 - 14:11

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01.04.2022
17:04 CancerNetwork.com OncView™ Podcast: Immunotherapy Response Monitoring in Lung Cancer

In an OncView program, Roy Herbst, MD, PhD, touched on clinical decision-making, monitoring response, and the potential treatment options available for treating non–small cell lung cancer.

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31.03.2022
22:50 ScienceDaily.com Researchers identify new targets for immunotherapy in colon cancer

Scientists identify a pathway of immune cell inhibition that may provide the basis for novel approaches to immunotherapy of colon cancer. Their results also highlight important roles of the intestinal microbiota in the development of the disease.

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19:32 Technology.org How Obesity Can Rewire the Immune System and the Response to Immunotherapy – and How to Change That

When mice with atopic dermatitis – a common type of allergic skin inflammation – are treated with drugs

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19:03 Technology.org How Obesity Can Rewire the Immune System and the Response to Immunotherapy – and How to Change That

When mice with atopic dermatitis – a common type of allergic skin inflammation – are treated with drugs

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29.03.2022
15:03 CancerNetwork.com Laurence Albigès, MD, PhD, on the Potential Impact of Immunotherapy-Based Combinations in Advanced RCC

Laurence Albigès, MD, PhD, discusses how immunotherapy combinations have affected the treatment landscape for previously untreated advanced or metastatic renal cell carcinoma.

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26.03.2022
03:44 News-Medical.Net New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

A new clinical trial at the University of Cincinnati is studying the effectiveness of a new two-pronged immunotherapy treatment procedure to treat the most aggressive and deadly type of brain tumors, called glioblastomas. Originating from healthy brain cells, glioblastomas can form in any area of the brain.

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23.03.2022
23:19 ScienceDaily.com FDA approved new immunotherapy regimen for patients with melanoma

The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer.

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20.03.2022
07:08 News-Medical.Net Trial shows safety and immunogenicity of immunotherapy with chemoradiation in cervical cancer patients

A Phase I/Ib trial conducted by the National Cancer Institute (NCI) National Clinical Trials Network (NCTN) group NRG Oncology, NRG-GY017, concluded that the addition of the immunotherapy drug atezolizumab prior to and concurrently given with chemoradiation (CRT) treatment was safe for women with node-positive, locally advanced cervical cancer.

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19.03.2022
05:37 Medscape.Com FDA Approves New Immunotherapy Combo for Melanoma

Nivolumab plus relatlimab might be a new standard of care.

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18.03.2022
19:07 Technology.org Enzyme could be new target for cancer immunotherapies

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new

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16:49 ScienceDaily.com Radical increase in the effectiveness of breast cancer immunotherapy

Researchers have discovered the essential role of a new factor, LCOR, in enabling cancer cells to present tumor antigens on their surfaces. These antigens allow the immune system to recognize the tumor, an essential step if immunotherapy treatment is to succeed. On the other hand, they have shown that cancer stem cells have very low levels of LCOR, making them invisible to the immune system and therefore resistant to treatment.

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05:44 News-Medical.Net New approach radically increases the success of breast cancer immunotherapy

A study published in the journal Nature Cancer, carried out within the Cancer Programme at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) by the Cancer Stem Cells and Metastasis Dynamics Laboratory, led by Dr. Toni Celià-Terrassa, and the Laboratory of Molecular Cancer Therapy, coordinated by Dr. Joan Albanell, with the participation of international centers, has discovered an approach that radically increases the success of immunotherapy in one of the most aggressive types of tumors, triple-negative breast cancer.

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17.03.2022
16:03 Technology.org LLNL study on tumor/immune cell interaction could impact cancer immunotherapies

Lawrence Livermore National Laboratory (LLNL) scientists exploring the interaction between cancer cells and the extracellular matrix (ECM) — the

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09:29 Technology.org LLNL study on tumor/immune cell interaction could impact cancer immunotherapies

Lawrence Livermore National Laboratory (LLNL) scientists exploring the interaction between cancer cells and the extracellular matrix (ECM) — the

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03:26 ScienceDaily.com A potential new target for cancer immunotherapies

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a new study.

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08.03.2022
15:09 Technology.org Novel treatment makes pancreatic cancer susceptible to immunotherapy, mouse study shows

Pancreatic cancer is one of the most aggressive and deadly tumor types and notorious for its resistance to

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14:09 Technology.org Researchers Pioneer Cancer-Fighting Immunotherapies that Infuse Hope

Pioneering researchers at the University of Virginia Cancer Center are developing innovative ways to supercharge our natural immune

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03:04 News-Medical.Net New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Pancreatic cancer is one of the most aggressive and deadly tumor types and notorious for its resistance to virtually all types of treatment, including newer immunotherapies.

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07.03.2022
22:21 ScienceDaily.com Novel treatment makes pancreatic cancer susceptible to immunotherapy, mouse study shows

A new study -- in mice -- suggests that blocking a major inflammatory pathway that is activated in pancreatic cancer makes the tumors sensitive to chemotherapy and a type of immunotherapy that prompts the immune system's T cells to attack the cancer cells. The therapy more than doubled survival in a mouse model of pancreatic cancer.

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19:15 ScienceDaily.com Is it working? Scientists say gene variant indicates effectiveness of immunotherapy for allergies

Although sublingual immunotherapy (SLIT) has become an effective treatment option for many allergies, about 20-30 percent of patients don't respond to SLIT for Japanese cedar pollinosis -- a highly common disease. In a recent study, scientists reported that a specific variant of the HLA-DPB1 gene is associated with poor response to this treatment, highlighting the potential of this and similar genes as relevant biomarkers in clinical practice for predicting one's responsiveness to allergen immunotherapy.

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06.03.2022
20:00 News-Medical.Net Melanoma patients do better on immunotherapy than completion lymph node dissection

For years, surgery for patients with stage III melanoma -; melanoma that has spread to the lymph nodes -; involved removing those lymph nodes along with the primary tumor.

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03.03.2022
14:42 News-Medical.Net Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

The discrepancy between preclinical advances in breast cancer immunotherapy and poor patient outcomes is rooted in the limitations of current breast cancer models. These models often fail to mimic complex interactions between cancer cells and key immune cells present in the tumor microenvironment.

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02.03.2022
13:36 Technology.org Scaffolding Tumor Formation Sets the Stage for Better Immunotherapies

The discrepancy between preclinical advances in breast cancer immunotherapy and poor patient outcomes is rooted in the limitations

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13:00 Technology.org Scaffolding Tumor Formation Sets the Stage for Better Immunotherapies

The discrepancy between preclinical advances in breast cancer immunotherapy and poor patient outcomes is rooted in the limitations

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01.03.2022
19:41 Technology.org For cancer patients on immunotherapy, harmful gut bacteria might matter more than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on

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08:56 News-Medical.Net Adding immunotherapy drug to standard head and neck cancer treatment increases patient survival

A University of Cincinnati clinical trial that added an immunotherapy drug to standard of care treatment regimens has shown increased survival rates for head and neck cancer patients with intermediate risk features.

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06:48 ScienceDaily.com For cancer patients on immunotherapy, harmful gut bacteria might matter more than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

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01:57 ScienceDaily.com Immunotherapy drug bolsters head and neck cancer treatment

A clinical trial has shown that the immunotherapy drug pembrolizumab increased survival rates for head and neck cancer patients with intermediate risk.

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28.02.2022
20:50 News-Medical.Net Understanding the gut microbiome could help personalize immunotherapy for melanoma

The largest study to date has confirmed the link between the gut microbiome and the response to cancer immunotherapy therapy for melanoma.

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19:34 News-Medical.Net Researchers develop new precision medicine technology for cancer immunotherapy

In recent years, great advances have been made in the development of new successful immunotherapies to treat cancer. CAR T-cell therapy and antibody treatments are two types of targeted immunotherapies that have revolutionized areas of cancer care.

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14:50 News-Medical.Net Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Researchers generated a panel of bnAbs against SARS-CoV, SARS-CoV-2, and its variant VOCs, including Omicron from sequentially immunized mice.

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